Imaging osteoarthritis in the knee joints using x-ray guided diffuse optical tomography

Qizhi Zhang; Zhen Yuan; Eric S. Sobel; Huabei Jiang

doi:10.1117/12.853402

2 March 2010 Imaging osteoarthritis in the knee joints using x-ray guided diffuse optical tomography

Qizhi Zhang, Zhen Yuan, Eric S. Sobel, Huabei Jiang

Proceedings Volume 7548, Photonic Therapeutics and Diagnostics VI; 75484J (2010) https://doi.org/10.1117/12.853402
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

In our previous studies, near-infrared (NIR) diffuse optical tomography (DOT) had been successfully applied to imaging osteoarthritis (OA) in the finger joints where significant difference in optical properties of the joint tissues was evident between healthy and OA finger joints. Here we report for the first time that large joints such as the knee can also be optically imaged especially when DOT is combined with x-ray tomosynthesis where the 3D image of the bones from x-ray is incorporated into the DOT reconstruction as spatial a priori structural information. This study demonstrates that NIR light can image large joints such as the knee in addition to finger joints, which will drastically broaden the clinical utility of our x-ray guided DOT technique for OA diagnosis.

Citation Download Citation

Qizhi Zhang, Zhen Yuan, Eric S. Sobel, and Huabei Jiang "Imaging osteoarthritis in the knee joints using x-ray guided diffuse optical tomography", Proc. SPIE 7548, Photonic Therapeutics and Diagnostics VI, 75484J (2 March 2010); https://doi.org/10.1117/12.853402

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available