Monitoring of tissue perfusion during esophagectomies with optical fiber probe spectroscopy

Dan Gareau; John Hunter M.D.; Steven Jacques

doi:10.1117/12.843705

22 February 2010 Monitoring of tissue perfusion during esophagectomies with optical fiber probe spectroscopy

Dan Gareau, John Hunter M.D., Steven Jacques

Proceedings Volume 7555, Advanced Biomedical and Clinical Diagnostic Systems VIII; 75551C (2010) https://doi.org/10.1117/12.843705
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

The specific optical spectra of tissues contain information about the biochemical composition. We present a simple optical fiber probe spectrometer design for noninvasive measurement of oxygen saturation in the microvasculature of stomach tissue. In a human Esophagectomy model with 23 patients, we measured the spectrum following surgical ligation of two of the three arterial paths to the stomach tissue that will become the anastamosis. Combining a diffusion model for semi-infinite slab remittance with absorption spectroscopy, we are able to specify the ratio of oxy-hemoglobin to deoxy-hemoglobin present in the tissue. We show a resting state of 0.47 (oxy-hemaglobin/total-hemaglobin) saturation decrease of 29% (p < 0.01) when arterial supply is reduced by artery ligation.

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Dan Gareau, John Hunter M.D., and Steven Jacques "Monitoring of tissue perfusion during esophagectomies with optical fiber probe spectroscopy", Proc. SPIE 7555, Advanced Biomedical and Clinical Diagnostic Systems VIII, 75551C (22 February 2010); https://doi.org/10.1117/12.843705

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KEYWORDS

Tissues

Blood

Tissue optics

Arteries

Surgery

Oxygen

Optical fibers

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