UV extended supercontinuum source for time resolved and steady state spectroscopy for biological and chemical molecules

R. R. Alfano; V. Kartazaev; I. Zeylikovich; B. Das; D. Nolan

doi:10.1117/12.842085

11 February 2010 UV extended supercontinuum source for time resolved and steady state spectroscopy for biological and chemical molecules

R. R. Alfano, V. Kartazaev, I. Zeylikovich, B. Das, D. Nolan

Author Affiliations +

Proceedings Volume 7561, Optical Biopsy VII; 756107 (2010) https://doi.org/10.1117/12.842085
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

The spectrum of the supercontinuum generated by a femtosecond Ti:Sapphire laser beam in photonic crystal fiber (PCF) is increased into the UV using small core diameter PCF with zero dispersion wavelength (ZDW) shorter 600 nm. A flat spectrum is generated that spans from 350 to 1000 nm. The SC was used as an excitation source for fluorescence spectroscopy. Fluorescence spectra can be detected from dye molecules, and native molecules in tissues samples with excitation from wavelengths extracted from ultrafast SC light in the spectral range between 350 to 500 nm using narrow bandpass filters. A Streak Camera was used for time-resolved fluorescence measurements.

Citation Download Citation

R. R. Alfano, V. Kartazaev, I. Zeylikovich, B. Das, and D. Nolan "UV extended supercontinuum source for time resolved and steady state spectroscopy for biological and chemical molecules", Proc. SPIE 7561, Optical Biopsy VII, 756107 (11 February 2010); https://doi.org/10.1117/12.842085

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