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23 February 2010 Monte Carlo modeling for photoacoustic-based transport-regime optical property estimation
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Abstract
We developed a unique reflection-mode photoacoustic technique sensitive to optical scattering in turbid media. We focused a small laser spot on to the surface of a turbid medium and captured the photoacoustic signal by a focused ultrasound transducer. The amplitude of the photoacoustic signal for different surface illumination spot locations is an effective estimate of the Green's function of light transport in turbid media. Our results for different concentrations of Intralipid indicate that this method is capable of distinguishing small changes in the reduced scattering coefficient. In this work, we present experimental measurements for an Intralipid phantom with reduced scattering coefficients of 3, 4, and 5 cm-1, and show that Monte Carlo simulations of light transport accurately reproduce experimental curves. This means that we can estimate transport-regime optical properties of the media given a suitable fitting algorithm.
© (2010) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Janaka C. Ranasinghesagara and Roger J. Zemp "Monte Carlo modeling for photoacoustic-based transport-regime optical property estimation", Proc. SPIE 7564, Photons Plus Ultrasound: Imaging and Sensing 2010, 75640F (23 February 2010); https://doi.org/10.1117/12.842038
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