Photoacoustic correlation technique for low-speed flow measurement

Sung-Liang Chen; Tao Ling; Sheng-Wen Huang; Hyoung Won Baac; Yu-Chung Chang; L. Jay Guo

doi:10.1117/12.840123

23 February 2010 Photoacoustic correlation technique for low-speed flow measurement

Sung-Liang Chen, Tao Ling, Sheng-Wen Huang, Hyoung Won Baac, Yu-Chung Chang, L. Jay Guo

Proceedings Volume 7564, Photons Plus Ultrasound: Imaging and Sensing 2010; 75642I (2010) https://doi.org/10.1117/12.840123
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

A photoacoustic correlation spectroscopy (PACS) technique was proposed for the first time. This technique is inspired by its optical counterpart-the fluorescence correlation spectroscopy (FCS), which is widely used in the characterization of the dynamics of fluorescent species. The fluorescence intensity is measured in FCS while the acoustic signals are detected in PACS. To proof of concept, we demonstrated the flow measurement of light-absorbing beads probed by a pulsed laser. A PACS system with temporal resolution of 0.8 sec was built. Polymer microring resonators were used to detect the photoacoustic signals, which were then signal processed and used to obtain the autocorrelation curves. Flow speeds ranging from 249 to 15.1 μm/s with corresponding flow time from 4.42 to 72.5 sec were measured. The capability of low-speed flow measurement can potentially be used for detecting blood flow in relatively deep capillaries in biological tissues. Moreover, similar to FCS, PACS may have many potential applications in studying the dynamics of photoacoustic beads.

Citation Download Citation

Sung-Liang Chen, Tao Ling, Sheng-Wen Huang, Hyoung Won Baac, Yu-Chung Chang, and L. Jay Guo "Photoacoustic correlation technique for low-speed flow measurement", Proc. SPIE 7564, Photons Plus Ultrasound: Imaging and Sensing 2010, 75642I (23 February 2010); https://doi.org/10.1117/12.840123

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