Optimization of the acousto-optic signal detection in cylindrical geometry

Sonny Gunadi; Samuel Powell; Clare E. Elwell; Terence S. Leung

doi:10.1117/12.842175

23 February 2010 Optimization of the acousto-optic signal detection in cylindrical geometry

Sonny Gunadi, Samuel Powell, Clare E. Elwell, Terence S. Leung

Proceedings Volume 7564, Photons Plus Ultrasound: Imaging and Sensing 2010; 756431 (2010) https://doi.org/10.1117/12.842175
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

The use of ultrasonic tagging of multiple scattered photons within turbid media for tomographic imaging is typically performed using optical detection in transmission mode. This study aimed to optimize the detection of the acousto-optic (AO) signal in cylindrical geometry, with a view to using the technique to measure blood oxygenation in the internal jugular vein of infants in the future. In our experiments, homogeneous phantoms of multiple transport scattering coefficients were constructed for the described geometry mimicking the infant neck. The optical source was systematically repositioned at different angles relative to the optical detector and the resulting AO signal was measured. The experimental results were also compared to focused ultrasound AO Monte Carlo (MC) simulation results. It was found that the optimal modulation depth and noise variance were highly dependent on the overlap region between the optical path length of the optical source-detector pair and the ultrasound focal zone. Therefore the optimal positions for both the optical and ultrasound probes could be estimated from both experimental and simulation results for a given geometry.

Citation Download Citation

Sonny Gunadi, Samuel Powell, Clare E. Elwell, and Terence S. Leung "Optimization of the acousto-optic signal detection in cylindrical geometry", Proc. SPIE 7564, Photons Plus Ultrasound: Imaging and Sensing 2010, 756431 (23 February 2010); https://doi.org/10.1117/12.842175

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