Guided-mode resonance sensor system for early detection of ovarian cancer

Debra Wawro; Peter Koulen; Yiwu Ding; Shelby Zimmerman; Robert Magnusson

doi:10.1117/12.842725

Translator Disclaimer

25 February 2010 Guided-mode resonance sensor system for early detection of ovarian cancer

Debra Wawro, Peter Koulen, Yiwu Ding, Shelby Zimmerman, Robert Magnusson

Author Affiliations +

Proceedings Volume 7572, Optical Diagnostics and Sensing X: Toward Point-of-Care Diagnostics; 75720D (2010) https://doi.org/10.1117/12.842725
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

A high-accuracy sensor system has been developed that provides near-instantaneous detection of biomarker proteins as indicators of ovarian serous papillary carcinoma. Based upon photonic guided-mode resonance technology, these highresolution sensors employ multiple resonance peaks to rapidly test for relevant proteins in complex biological samples. This label-free sensor approach requires minimal sample processing and has the capability to measure multiple agents simultaneously and in real time. A detection system has been developed and performance characterized. Identification and quantification of protein biomarkers that are up- or downregulated in blood and serum as indicators of ovarian cancer will be presented.

Citation Download Citation

Debra Wawro, Peter Koulen, Yiwu Ding, Shelby Zimmerman, and Robert Magnusson "Guided-mode resonance sensor system for early detection of ovarian cancer", Proc. SPIE 7572, Optical Diagnostics and Sensing X: Toward Point-of-Care Diagnostics, 75720D (25 February 2010); https://doi.org/10.1117/12.842725

ACCESS THE FULL ARTICLE