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Three types of photo-responsive nano-architectures -nano-gatekeepers, nanovalves and nanoimpellers- were synthesized
based on azobenzene derivatives tethered in and on mesporous silica nanoparticles. The light responsive nature of these
materials enables them to be externally controlled such that transport of the cargo molecules from mesopores can be
regulated. In particular, nanoimpellers have shown to successfully release anti-cancer drug, camptothecin, upon
photoactivation and ultimately led to cell apoptosis.
Yuen A Lau,Daniel P. Ferris, andJeffrey I. Zink
"Photo-driven nano-impellers and nanovalves for on-command drug release", Proc. SPIE 7574, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VII, 75740P (1 March 2010); https://doi.org/10.1117/12.841175
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Yuen A Lau, Daniel P. Ferris, Jeffrey I. Zink, "Photo-driven nano-impellers and nanovalves for on-command drug release," Proc. SPIE 7574, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VII, 75740P (1 March 2010); https://doi.org/10.1117/12.841175