Paper
23 February 2010 Femtosecond nanomachining: theory and applications in biomedical research and analysis
Alan J. Hunt, Jeffrey F. Herbstman
Author Affiliations +
Abstract
The nonlinear mechanisms of femtosecond laser damage allow tight control of ablation to precisely remove very small amounts of material, leaving holes as small as tens of nanometers wide. By serially targeting laser pulses in glass, a host of three dimensional nano- and microfluidic structures can be formed including nozzles, mixers, and separation columns. Recent advances allow the formation of high aspect ratio nanochannels from single pulses, thus helping address fabrication speed limitations presented by serial processing. Femtosecond nanomachining is enabling for a variety of applications including nanoscale devices for analytic separations, chemical analysis, and biomedical diagnostics.
© (2010) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Alan J. Hunt and Jeffrey F. Herbstman "Femtosecond nanomachining: theory and applications in biomedical research and analysis", Proc. SPIE 7585, Laser-based Micro- and Nanopackaging and Assembly IV, 75850L (23 February 2010); https://doi.org/10.1117/12.843688
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KEYWORDS
Femtosecond phenomena

Microfluidics

Glasses

Chemical analysis

Nanolithography

Biological research

Biomedical optics

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