A novel quantitative imaging technique for material differentiation based on differential phase contrast CT

Zhihua Qi; Joseph Zambelli; Nicholas Bevins; Guang-Hong Chen

doi:10.1117/12.844536

22 March 2010 A novel quantitative imaging technique for material differentiation based on differential phase contrast CT

Zhihua Qi, Joseph Zambelli, Nicholas Bevins, Guang-Hong Chen

Author Affiliations +

Proceedings Volume 7622, Medical Imaging 2010: Physics of Medical Imaging; 76220O (2010) https://doi.org/10.1117/12.844536
Event: SPIE Medical Imaging, 2010, San Diego, California, United States

Abstract

Compared to single energy CT, which provides information only about the x-ray linear attenuation coefficients, dual energy CT is able to obtain the electron density and effective atomic number for different materials in a quantitative way. In this study, as an alternative to dual energy CT, a novel quantitative imaging method based on phase contrast CT is described. Rather than requiring two scans with different x-ray photon energies, diffraction grating-based phase contrast CT is capable of reconstructing images of both the linear attenuation and refractive index decrement from a single scan. From the two images, quantitative information of both the electron density and effective atomic number can be extracted. Experimental results demonstrate that: (1) electron density can be accurately determined from refractive index decrement through a linear relationship; and (2) effective atomic number can be explicitly derived from the ratio of linear attenuation to refractive index decrement, using a simple function, i.e., a power function plus a constant. The presented method will shed insight into the field of material separation and find its use in medical and non-medical applications.

Citation Download Citation

Zhihua Qi, Joseph Zambelli, Nicholas Bevins, and Guang-Hong Chen "A novel quantitative imaging technique for material differentiation based on differential phase contrast CT", Proc. SPIE 7622, Medical Imaging 2010: Physics of Medical Imaging, 76220O (22 March 2010); https://doi.org/10.1117/12.844536

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE