Extending the detectability index to quantitative imaging performance: applications in tomosynthesis and CT

Samuel Richard; Baiyu Chen; Ehsan Samei

doi:10.1117/12.845286

23 March 2010 Extending the detectability index to quantitative imaging performance: applications in tomosynthesis and CT

Samuel Richard, Baiyu Chen, Ehsan Samei

Author Affiliations +

Proceedings Volume 7622, Medical Imaging 2010: Physics of Medical Imaging; 76220Z (2010) https://doi.org/10.1117/12.845286
Event: SPIE Medical Imaging, 2010, San Diego, California, United States

Abstract

This study aimed to extend Fourier-based imaging metrics for the modeling of quantitative imaging performance. Breast tomosynthesis was used as a platform for investigating acquisition and processing parameters (e.g., acquisition angle and dose) that can significantly affect 3D signal and noise, and consequently quantitative imaging performance. The detectability index was computed using the modulation transfer function and noise-power spectrum combined with a Fourier description of imaging task. Three imaging tasks were considered: detection, area estimation (in coronal slice), and volume estimation of a 4 mm diameter spherical target. Task functions for size estimation were generated by using measured performance of the maximum-likelihood estimator as training data. The detectability index computed with the size estimation tasks correlated well with precision measurements for area and volume estimation over a fairly broad range of imaging conditions and provided a meaningful figure of merit for quantitative imaging performance. Furthermore, results highlighted that optimal breast tomosynthesis acquisition parameters depend significantly on imaging task. Mass detection was optimal at an acquisition angle of 85° while area and volume estimation for the same mass were optimal at ~100° and 125° acquisition angles, respectively. These findings provide key initial validation that the Fourier-based detectability index extended to estimation tasks can represent a meaningful metric and predictor of quantitative imaging performance.

Citation Download Citation

Samuel Richard, Baiyu Chen, and Ehsan Samei "Extending the detectability index to quantitative imaging performance: applications in tomosynthesis and CT", Proc. SPIE 7622, Medical Imaging 2010: Physics of Medical Imaging, 76220Z (23 March 2010); https://doi.org/10.1117/12.845286

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE