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Bony structures at the skull base were the main obstacle to detection and estimation of arterial stenoses and aneurysms
for CT angiography in the brain. Direct subtraction and the matched mask bone elimination (MMBE) have become two
standard methods for removing bony structures. However, clinicians regularly find that calcified plaques at or near the
carotid canal cannot be removed satisfactorily by existing methods. The blood-plaque boundary tends to be blurred by
subtraction operation while plaque size is constantly overestimated by the bone mask dilation operation in the MMBE
approach. In this study, we propose using the level of enhancement to adjust the MMBE bone mask more intelligently
on the artery- and tissue-bone/plaque boundaries. The original MMBE method is only applied to the tissue-bone
boundary voxels; while the artery-bone/blood-plaque boundary voxels, identified by a higher enhancement level, are
processed by direct subtraction instead. A dataset of 6 patients (3 scanned with a regular dose and 3 scanned with a
reduced dose) with calcified plaques at or near the skull base is used to examine our new method. Preliminary results
indicate that the visualization of intracranial arteries with calcified plaques at the skull base can be improved effectively
and efficiently.
Adam Huang,Chung-Wei Lee,Chung-Yi Yang, andHon-Man Liu
"Improving visualization of intracranial arteries at the skull base for CT angiography with calcified plaques", Proc. SPIE 7626, Medical Imaging 2010: Biomedical Applications in Molecular, Structural, and Functional Imaging, 76260E (9 March 2010); https://doi.org/10.1117/12.844065
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Adam Huang, Chung-Wei Lee, Chung-Yi Yang, Hon-Man Liu, "Improving visualization of intracranial arteries at the skull base for CT angiography with calcified plaques," Proc. SPIE 7626, Medical Imaging 2010: Biomedical Applications in Molecular, Structural, and Functional Imaging, 76260E (9 March 2010); https://doi.org/10.1117/12.844065