Framework design and development of an informatics architecture for a systems biology approach to traumatic brain injury

Adil Alaoui; Dongkyu Kim; Betty Levine; Kevin Cleary; Howard J. Federoff; Timothy Mhyre

doi:10.1117/12.846090

11 March 2010 Framework design and development of an informatics architecture for a systems biology approach to traumatic brain injury

Adil Alaoui, Dongkyu Kim, Betty Levine, Kevin Cleary, Howard J. Federoff, Timothy Mhyre

Author Affiliations +

Proceedings Volume 7628, Medical Imaging 2010: Advanced PACS-based Imaging Informatics and Therapeutic Applications; 76280N (2010) https://doi.org/10.1117/12.846090
Event: SPIE Medical Imaging, 2010, San Diego, California, United States

Abstract

Traumatic Brain Injury (TBI) is a problem of major medical and socioeconomic significance, although the pathogenesis of its sequelae is not completely understood. As part of a large, multi-center project to study mild and moderate TBI, a database and informatics system to integrate a wide-range of clinical, biological, and imaging data is being developed. This database constitutes a systems-based approach to TBI with the goals of developing and validating biomarker panels that might be used to diagnose brain injury, predict clinical outcome, and eventually develop improved therapeutics. This paper presents the architecture for an informatics system that stores the disparate data types and permits easy access to the data for analysis.

Citation Download Citation

Adil Alaoui, Dongkyu Kim, Betty Levine, Kevin Cleary, Howard J. Federoff, and Timothy Mhyre "Framework design and development of an informatics architecture for a systems biology approach to traumatic brain injury", Proc. SPIE 7628, Medical Imaging 2010: Advanced PACS-based Imaging Informatics and Therapeutic Applications, 76280N (11 March 2010); https://doi.org/10.1117/12.846090

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