Clinical diagnosis of oral submucous fibrosis with optical coherence tomography

Cheng-Kuang Lee; Meng-Tsan Tsai; C. C. Yang; Chun-Pin Chiang

doi:10.1117/12.852410

25 November 2009 Clinical diagnosis of oral submucous fibrosis with optical coherence tomography

Cheng-Kuang Lee, Meng-Tsan Tsai, C. C. Yang, Chun-Pin Chiang

Proceedings Volume 7634, Optical Sensors and Biophotonics; 763405 (2009) https://doi.org/10.1117/12.852410
Event: Asia Communications and Photonics, 2009, Shanghai, Shanghai , China

Abstract

A swept-source optical coherence tomography (SS-OCT) system with a specially designed probe is built for clinical scanning of oral submucous fibrosis (OSF) patients. By analysing 44 OSF cases of SS-OCT scanning results, two indicators, including epithelium (EP) thickness and standard deviation (SD) of A-mode scan intensity in the laminar propria (LP) layer, are found useful for real-time OSF diagnosis. Statistics show that sensitivity and specificity of LP SD can reach 84.1 and 95.5 %, respectively. Also, both sensitivity and specificity of EP thickness can reach 100 %.

Citation Download Citation

Cheng-Kuang Lee, Meng-Tsan Tsai, C. C. Yang, and Chun-Pin Chiang "Clinical diagnosis of oral submucous fibrosis with optical coherence tomography", Proc. SPIE 7634, Optical Sensors and Biophotonics, 763405 (25 November 2009); https://doi.org/10.1117/12.852410

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