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23 April 2010 High reliability, miniature personal hypoxia monitoring system
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In this work, we present research performed towards the realization of a hypoxia monitor that can detect the onset of hypoxia within a minute with very low false positive and false negative rates. We report the development of the next-generation hypoxia monitor with the capability to simultaneously detect various physiological parameters that change in response to reduced oxygen availability and identify the onset of hypoxia based on the changes in their cross-correlation signals. Significant improvements are obtained over the conventional techniques that are used currently to measure some of the physiological parameters including blood oxygen saturation and blood flow velocity. We demonstrate that a simple patch geometry holding three LEDs and two single photon sensitive detectors can be used to simultaneously obtain the heart rate, respiratory rate, blood flow velocity and blood oxygen saturation levels and in less than one minute analyze their cross-correlation signals to identify the onset of hypoxia from the more benign auto-regulatory response to stress.
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Rajan Gurjar, Madhavi Seetamraju, David E. Wolf, and John Hastings "High reliability, miniature personal hypoxia monitoring system", Proc. SPIE 7674, Smart Biomedical and Physiological Sensor Technologies VII, 76740H (23 April 2010);

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