The impact of laser irradiation during antimicrobial photodynamic therapy in an artificial biofilm model

Martin Schneider; Gregor Kirfel; Michael Berthold; Olivier Brede; Matthias Frentzen; Andreas Braun

doi:10.1117/12.873792

18 February 2011 The impact of laser irradiation during antimicrobial photodynamic therapy in an artificial biofilm model

Martin Schneider, Gregor Kirfel, Michael Berthold, Olivier Brede, Matthias Frentzen, Andreas Braun

Author Affiliations +

Proceedings Volume 7884, Lasers in Dentistry XVII; 78840W (2011) https://doi.org/10.1117/12.873792
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

The aim of the study was to assess the impact of laser irradiation during antimicrobial photodynamic therapy. Test chambers containing each a salivary pellicle layer and a Stretococcus mutans culture were analyzed using confocal laser microscopy after adding a photosensitizer. Half of the chambers were irradiated with a diode laser. Comparing baseline fluorescence with the values after laser irradiation, a decrease of fluorescence could be observed. The non-irradiated group showed a slight increase of fluorescence. The present study indicates that laser irradiation is an essential part to reduce bacteria by antimicrobial photodynamic therapy.

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Martin Schneider, Gregor Kirfel, Michael Berthold, Olivier Brede, Matthias Frentzen, and Andreas Braun "The impact of laser irradiation during antimicrobial photodynamic therapy in an artificial biofilm model", Proc. SPIE 7884, Lasers in Dentistry XVII, 78840W (18 February 2011); https://doi.org/10.1117/12.873792

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