Full-field optical coherence tomography for rapid 3-D imaging in biological systems

Wei Zheng; Colin J. R. Sheppard

doi:10.1117/12.874895

8 March 2011 Full-field optical coherence tomography for rapid 3-D imaging in biological systems

Wei Zheng, Colin J. R. Sheppard

Proceedings Volume 7889, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV; 78892M (2011) https://doi.org/10.1117/12.874895
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

Full-field optical coherence tomography (FF-OCT) is an emerging non-invasive, label-free, interferometric technique for 3D imaging of biomedical objects with micron-scale resolutions. The conventional phase-shifting technique in FF-OCT involves in mechanically moving a mirror to change the optical path difference for obtaining en face OCT images, but with the use of a broadband source in FF-OCT, the phase shifts of different spectral components are not the same, resulting in the ambiguities in 3-D image reconstruction. In this study, we propose to utilize the ferroelectric liquid crystal (FLC) device-controlled geometric phase shifting technique to realize achromatic phase shifting for rapid 3-D imaging. We demonstrate this FLC-controlled FF-OCT technique by imaging biological samples (e.g., onion tissue).

Citation Download Citation

Wei Zheng and Colin J. R. Sheppard "Full-field optical coherence tomography for rapid 3-D imaging in biological systems", Proc. SPIE 7889, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV, 78892M (8 March 2011); https://doi.org/10.1117/12.874895

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KEYWORDS

Optical coherence tomography

Imaging systems

Image resolution

Beam splitters

Phase shifts

Ferroelectric LCDs

Light sources

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