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16 February 2011 Modification of a long period grating-based fiber optic for DNA biosensing
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Abstract
The feasibility of a biosensor for DNA label-free detection, based on long period fiber gratings, has been investigated. The surface of the grating has been functionalized with Peptide Nucleic Acid (PNA) probes. DNA strands, matched with the PNA probes, have been immobilized on the surface itself. The possibility of a resonant wavelength shift in the transmission spectrum due to the DNA capture will be discussed. The problem of reusing the sensor for multiple measurements will also be addressed.
© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
M. Sozzi, A. Cucinotta, R. Corradini, R. Marchelli, M. Konstantaki, S. Pissadakis, and S. Selleri "Modification of a long period grating-based fiber optic for DNA biosensing", Proc. SPIE 7894, Optical Fibers, Sensors, and Devices for Biomedical Diagnostics and Treatment XI, 78940J (16 February 2011); https://doi.org/10.1117/12.874458
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