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16 February 2011Three dimensional localization of cancerous prostate tissue using backscattering scanning polarization imaging and independent component analysis
Three-dimensional (3D) localization of human cancerous prostate tissue embedded in normal prostate tissue was
demonstrated and characterized using backscattering scanning polarization imaging and independent component analysis
(ICA). Backscattering two-dimensional (2D) images of a tissue sample illuminated with a raster scanning laser beam
were recorded using a CCD camera to obtain multiple angular views of the target embedded inside the tissue medium.
The 3D location of the object was retrieved by matching the leading Independent Component(s) of intensity distribution
of images to the numerical propagation of the target to the surface of the tissue medium.
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Yang Pu, Wubao Wang, Min Xu, Guichen Tang, Yury Budansky, Robert R. Alfano, "Three dimensional localization of cancerous prostate tissue using backscattering scanning polarization imaging and independent component analysis," Proc. SPIE 7895, Optical Biopsy IX, 78950K (16 February 2011); https://doi.org/10.1117/12.873924