Second generation optical-resolution photoacoustic microscopy

Konstantin Maslov; Song Hu; Lihong V. Wang

doi:10.1117/12.874786

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22 February 2011 Second generation optical-resolution photoacoustic microscopy

Konstantin Maslov, Song Hu, Lihong V. Wang

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Proceedings Volume 7899, Photons Plus Ultrasound: Imaging and Sensing 2011; 789933 (2011) https://doi.org/10.1117/12.874786
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

We developed a second-generation optical-resolution photoacoustic microscope (OR-PAM) with a novel acoustic detection scheme, which improved upon the sensitivity of our first-generation system by 18 dB. Moreover, translating the imaging head instead of the living object improved the scanning speed by a factor of 5, widening the field of view within the same acquisition time. The anatomy and hemoglobin oxygen saturation of an entire mouse ear was imaged in vivo.

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Konstantin Maslov, Song Hu, and Lihong V. Wang "Second generation optical-resolution photoacoustic microscopy", Proc. SPIE 7899, Photons Plus Ultrasound: Imaging and Sensing 2011, 789933 (22 February 2011); https://doi.org/10.1117/12.874786

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