System-independent assessment of OCT axial resolution with a "bar chart" phantom

Anant Agrawal; Robert Chang; Megan Connors; Christopher Stafford; Jeeseong Hwang; Joshua Pfefer

doi:10.1117/12.880958

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10 February 2011 System-independent assessment of OCT axial resolution with a "bar chart" phantom

Anant Agrawal, Robert Chang, Megan Connors, Christopher Stafford, Jeeseong Hwang, Joshua Pfefer

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Proceedings Volume 7906, Optical Diagnostics and Sensing XI: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue III; 79060R (2011) https://doi.org/10.1117/12.880958
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

We present a optical phantom approach for the characterization of OCT axial resolution and contrast via multilayered "bar charts." We explored two methods to fabricate these phantoms: the first is based on monolayers of light-scattering microspheres with an intervening layer of transparent silicone, and the second involves alternating layers of scatteringenhanced silicone and transparent silicone. Varying the diameter of the microspheres and the thickness of the silicone layers permits different spatial frequencies to be realized in the axial dimension of the phantoms. Because the phantom's dimensions are accurately known independent of the OCT system, no information about the system's spatial calibration is required. We quantified the degree to which the bars in each phantom could be resolved with OCT, which provides insights into the axial contrast transfer function. Initial testing of these phantoms on time-resolved and Fourier-domain OCT platforms indicated that our approach can provide accurate, system-independent estimates of resolution.

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Anant Agrawal, Robert Chang, Megan Connors, Christopher Stafford, Jeeseong Hwang, and Joshua Pfefer "System-independent assessment of OCT axial resolution with a "bar chart" phantom", Proc. SPIE 7906, Optical Diagnostics and Sensing XI: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue III, 79060R (10 February 2011); https://doi.org/10.1117/12.880958

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