A novel wireless Love wave biosensor platform for multifunctional detection

Taehyeon Song; Minwoo Nam; SeungYeon Song; Hyun C. Yoon; Keekeun Lee

doi:10.1117/12.876098

28 February 2011 A novel wireless Love wave biosensor platform for multifunctional detection

Taehyeon Song, Minwoo Nam, SeungYeon Song, Hyun C. Yoon, Keekeun Lee

Proceedings Volume 7928, Reliability, Packaging, Testing, and Characterization of MEMS/MOEMS and Nanodevices X; 79280O (2011) https://doi.org/10.1117/12.876098
Event: SPIE MOEMS-MEMS, 2011, San Francisco, California, United States

Abstract

This paper presents a novel wireless Love wave biosensor platform for multi-functional detection. A 440MHz wireless and surface acoustic wave (SAW)-based biosensor was developed on a 41° YX LiNbO₃ piezoelectric substrate for the simultaneous detection of Anti- Dinitrophenyl-KLH (anti-DNP) immunoglobulin G (IgG). The developed biosensor was composed of a SAW reflective delay lines structured by an interdigital transducer (IDT), shorted grating reflectors, poly(methyl-methacrylate) (PMMA) layer and two sensitive films (Cr/Au). The PMMA was used for the waveguide layer. Coupling of mode (COM) modeling was conducted to determine the optimal device parameters prior to fabrication. The fabricated devices were wirelessly characterized by using the network analyzer as the reader unit. The binding of anti-DNP to DNP receptor molecules induced a change in phase shifts of the original reflection peaks due to a mass loading effect. The phase shifts increased linearly with increasing anti-DNP concentration. The measured reflective coefficient S11 in the time domain showed high signal/noise (S/N) ratio, small signal attenuation, and few spurious peaks. The time positions of the reflection peaks were well matched with the predicted values from the simulation. The obtained sensitivity was 167.9°/μg/ml and 44.8°/ μg/ml for the 1st and the 2nd sensing area, respectively.

Citation Download Citation

Taehyeon Song, Minwoo Nam, SeungYeon Song, Hyun C. Yoon, and Keekeun Lee "A novel wireless Love wave biosensor platform for multifunctional detection", Proc. SPIE 7928, Reliability, Packaging, Testing, and Characterization of MEMS/MOEMS and Nanodevices X, 79280O (28 February 2011); https://doi.org/10.1117/12.876098

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available