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8 February 2011 Optimization of waveguide structure for local evanescent field shift detection
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The waveguide structure for the local evanescent array coupled (LEAC) biosensor is optimized theoretically with Beam Propagation Method (BPM) simulations. The LEAC biosensor has successfully demonstrated experimental results of a sensitivity of 16% /nm and a metrology limit of 14 pm. Considering the waveguide thickness detector position used in previous experiments are far from optimized values, the detection performance of the LEAC sensor can be significantly improved with the simulated optimal structure. With the optimized parameters, when the upper cladding is air the estimated metrology limit is 0.8 pm; with water as the upper cladding for real-time measurements in an intigrated microfluidic channel, the estimated metrology limit is 1.6 pm.
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Zhangjing Yi, Rongjin Yan, Timothy A. Erickson, Rashid Safaisini, and Kevin L. Lear "Optimization of waveguide structure for local evanescent field shift detection", Proc. SPIE 7941, Integrated Optics: Devices, Materials, and Technologies XV, 79410L (8 February 2011);

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