Differential spectral imaging with gold nanorod light scattering labels

Le Qiu; Edward Vitkin; Lianyu Guo; Eugene B. Hanlon; Irving Itzkan; Lev T. Perelman

doi:10.1117/12.874240

24 January 2011 Differential spectral imaging with gold nanorod light scattering labels

Le Qiu, Edward Vitkin, Lianyu Guo, Eugene B. Hanlon, Irving Itzkan, Lev T. Perelman

Proceedings Volume 7945, Quantum Sensing and Nanophotonic Devices VIII; 79452E (2011) https://doi.org/10.1117/12.874240
Event: SPIE OPTO, 2011, San Francisco, California, United States

Abstract

Gold nanorods have the potential to be employed as extremely bright molecular marker labels. However, samples containing a large number of gold nanorods usually exhibit relatively wide spectral lines. This linewidth limits the use of the nanorods since it would be rather difficult to image several types of nanorod markers simultaneously. We measured native scattering spectra of single gold nanorods with the CLASS microscope and found that single gold nanorods have a narrow spectrum as predicted by the theory. That suggests that nanorod-based molecular markers with controlled narrow aspect ratios should provide spectral lines sufficiently narrow for effective biomedical imaging.

Citation Download Citation

Le Qiu, Edward Vitkin, Lianyu Guo, Eugene B. Hanlon, Irving Itzkan, and Lev T. Perelman "Differential spectral imaging with gold nanorod light scattering labels", Proc. SPIE 7945, Quantum Sensing and Nanophotonic Devices VIII, 79452E (24 January 2011); https://doi.org/10.1117/12.874240

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available