Improving the imaging ability of ultrasound-modulated optical tomography with spectral-hole burning

Xiao Xu; Honglin Liu; Lihong V. Wang

doi:10.1117/12.873999

10 February 2011 Improving the imaging ability of ultrasound-modulated optical tomography with spectral-hole burning

Xiao Xu, Honglin Liu, Lihong V. Wang

Proceedings Volume 7948, Advances in Photonics of Quantum Computing, Memory, and Communication IV; 794803 (2011) https://doi.org/10.1117/12.873999
Event: SPIE OPTO, 2011, San Francisco, California, United States

Abstract

Ultrasound-modulated optical tomography is a hybrid imaging technique based on detection of the diffused light modulated by a focused ultrasonic wave inside a scattering medium. With the combined advantages of ultrasonic resolution and optical contrast, UOT is ideal for deep tissue imaging. Its growth in popularity and application, however, is hindered by the low efficiency in detecting the modulated diffused photons. Research activities on UOT have therefore been centered on improving its signal detection efficiency by exploring various technical solutions. A prime example is the use of spectral-hole burning (SHB) in UOT. By applying SHB crystal as a spectral filter, one modulation sideband of the diffused light can be efficiently selected while all the other frequency components are strongly suppressed. Immune to both the spatial and temporal incoherence of the signal with a high enough on/off ratio, SHB can boost the UOT imaging ability dramatically and push it towards practical applications. We compare SHB with the other technologies that have been applied to UOT, and identify the unique features that make SHB a preferable tool for UOT. We also discuss the desired improvements from the SHB side, which will help UOT pave the way from research to everyday life.

Citation Download Citation

Xiao Xu, Honglin Liu, and Lihong V. Wang "Improving the imaging ability of ultrasound-modulated optical tomography with spectral-hole burning", Proc. SPIE 7948, Advances in Photonics of Quantum Computing, Memory, and Communication IV, 794803 (10 February 2011); https://doi.org/10.1117/12.873999

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available