New optical reference standard in the field of biology: interrogation of micro-resonator based biosensor with a phase sensitive-optical low coherence interferometer

A.-F. Obaton; J. Dubard

doi:10.1117/12.886690

6 May 2011 New optical reference standard in the field of biology: interrogation of micro-resonator based biosensor with a phase sensitive-optical low coherence interferometer

A.-F. Obaton, J. Dubard

Author Affiliations +

Proceedings Volume 8073, Optical Sensors 2011; and Photonic Crystal Fibers V; 80730L (2011) https://doi.org/10.1117/12.886690
Event: SPIE Optics + Optoelectronics, 2011, Prague, Czech Republic

Abstract

A phase-sensitive optical low coherence interferometer is investigated experimentally to implement a new optical reference standard in the field of biology. This interrogation technique is associated to a planar cyclic resonant sensor such as an optical waveguide-based micro-cavity. The biological solution to be analyzed will be brought onto the surface of the sensor through a micro-fluidic cell. The aim of this association is to quantify low concentrations of analytes and to realize a real-time investigation of the kinetics of specific molecules with time and temperature for metrological applications, with better sensitivity and accuracy than existing techniques. This paper deals with the results of a feasibility study on the PS-OLCI technique as a new reference in the field of biology.

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A.-F. Obaton and J. Dubard "New optical reference standard in the field of biology: interrogation of micro-resonator based biosensor with a phase sensitive-optical low coherence interferometer", Proc. SPIE 8073, Optical Sensors 2011; and Photonic Crystal Fibers V, 80730L (6 May 2011); https://doi.org/10.1117/12.886690

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