Gold @ silica core-shell nanoparticle for enhanced surface plasmon resonance detection of DNA hybridization in combination with gold nanowire gratings

Seyoung Moon; Youngjin Oh; Donghyun Kim; Hosub Lee; Hyun Chang Kim; Kangtaek Lee

doi:10.1117/12.894214

12 September 2011 Gold @ silica core-shell nanoparticle for enhanced surface plasmon resonance detection of DNA hybridization in combination with gold nanowire gratings

Seyoung Moon, Youngjin Oh, Donghyun Kim, Hosub Lee, Hyun Chang Kim, Kangtaek Lee

Author Affiliations +

Proceedings Volume 8099, Biosensing and Nanomedicine IV; 809914 (2011) https://doi.org/10.1117/12.894214
Event: SPIE NanoScience + Engineering, 2011, San Diego, California, United States

Abstract

Metallic nanoparticles have drawn much interest due to their distinct plasmonic characteristics especially in imaging and sensing applications. Surface plasmon resonance (SPR) based biosensors have evolved in many ways, among which sensitivity enhancement towards molecular sensing capability came up with strategies to overcome the hard limit of the intrinsic sensitivity of gold thin film. Recently adoption of signal contrast materials has proven successful in biochemical sensing applications. This study employs gold-SiO2 core-shell nanoparticles (CSNPs) as a strong SPR signal contrast agents. To reveal the underlying physics for the contrast mechanism, the particle characteristics were analytically evaluated in terms of light interaction coefficients. We experimentally demonstrate the effect of the CSNPs by applying them to acquire enhanced signal in DNA hybridization sensing scheme. We also applied gold nanowire grating structure on conventional gold thin film to further amplify the intrinsic sensitivity, where localized surface plasmon and locally amplified evanescent fields take parts. The results suggest that CSNPs and the grating structure cooperatively enhance the sensitivity and the role of nanowire gratings was analyzed with numerical methods to allow optimum sensitivity enhancement in terms of fill factor variations. The effects of field localization, amplification and enlarged signature of CSNPs are also discussed.

Citation Download Citation

Seyoung Moon, Youngjin Oh, Donghyun Kim, Hosub Lee, Hyun Chang Kim, and Kangtaek Lee "Gold @ silica core-shell nanoparticle for enhanced surface plasmon resonance detection of DNA hybridization in combination with gold nanowire gratings", Proc. SPIE 8099, Biosensing and Nanomedicine IV, 809914 (12 September 2011); https://doi.org/10.1117/12.894214

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
7 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Nanowires

Gold

Surface plasmons

Molecules

Nanoparticles

Resonance enhancement

Thin films

Show All Keywords

Keywords/Phrases

Search In:

Publication Years