Role of iNOS gene expression in the anti-inflammatory and tissue protective mechanisms of continuous wave at 630-905nm and 905nm superpulsed laser therapy

Arkady Mandel; Yumi Moriyama; Jamie Fong; Roger Dumoulin-White; Lothar Lilge

doi:10.1117/12.912200

9 March 2012 Role of iNOS gene expression in the anti-inflammatory and tissue protective mechanisms of continuous wave at 630-905nm and 905nm superpulsed laser therapy

Arkady Mandel, Yumi Moriyama, Jamie Fong, Roger Dumoulin-White, Lothar Lilge

Author Affiliations +

Proceedings Volume 8211, Mechanisms for Low-Light Therapy VII; 82110E (2012) https://doi.org/10.1117/12.912200
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

Up regulation of iNOS gene expression is playing a role in the initiation of the anti-inflammatory and tissue protective mechanisms related to nitric oxide (NO) for continuous wave red and infrared as well as 905nm superpulsed laser therapy (SPLT). The iNOS expression before and after laser therapy was evaluated in a zymosan-induced acute arthritis model, in knee joints of young (<15 weeks), middle aged (>15 weeks and < 35 weeks) and old (> 35 weeks) FVB/N-Tg (iNOS-luc) mice by bioluminescence imaging.

Citation Download Citation

Arkady Mandel, Yumi Moriyama, Jamie Fong, Roger Dumoulin-White, and Lothar Lilge "Role of iNOS gene expression in the anti-inflammatory and tissue protective mechanisms of continuous wave at 630-905nm and 905nm superpulsed laser therapy", Proc. SPIE 8211, Mechanisms for Low-Light Therapy VII, 82110E (9 March 2012); https://doi.org/10.1117/12.912200

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