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31 January 2012 Optoelectronic tweezers for medical diagnostics
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Abstract
Optoelectronic tweezers (OET) allows the spatial patterning of electric fields through selected illumination of a photoconductive surface. This enables the manipulation of micro particles and cells by creating non-uniform electrical fields that then produce dielectrophoretic (DEP) forces. The DEP responses of cells differ and can produce negative or positive (repelled or attracted to areas of high electric field) forces. Therefore OET can be used to manipulate individual cells and separate different cell types from each other. Thus OET has many applications for medical diagnostics, demonstrated here with work towards diagnosing Human African Trypanosomiasis, also known as sleeping sickness.
© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Clemens Kremer, Steven Neale, Anoop Menachery, Mike Barrett, and Jonathan M. Cooper "Optoelectronic tweezers for medical diagnostics", Proc. SPIE 8212, Frontiers in Biological Detection: From Nanosensors to Systems IV, 82120E (31 January 2012); https://doi.org/10.1117/12.903944
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