Time-reversal optical tomography: detecting and locating extended targets in a turbid medium

Binlin Wu; W. Cai; M. Xu; S. K. Gayen

doi:10.1117/12.906799

29 February 2012 Time-reversal optical tomography: detecting and locating extended targets in a turbid medium

Binlin Wu, W. Cai, M. Xu, S. K. Gayen

Proceedings Volume 8216, Multimodal Biomedical Imaging VII; 82160K (2012) https://doi.org/10.1117/12.906799
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

Time Reversal Optical Tomography (TROT) is developed to locate extended target(s) in a highly scattering turbid medium, and estimate their optical strength and size. The approach uses Diffusion Approximation of Radiative Transfer Equation for light propagation along with Time Reversal (TR) Multiple Signal Classification (MUSIC) scheme for signal and noise subspaces for assessment of target location. A MUSIC pseudo spectrum is calculated using the eigenvectors of the TR matrix T, whose poles provide target locations. Based on the pseudo spectrum contours, retrieval of target size is modeled as an optimization problem, using a "local contour" method. The eigenvalues of T are related to optical strengths of targets. The efficacy of TROT to obtain location, size, and optical strength of one absorptive target, one scattering target, and two absorptive targets, all for different noise levels was tested using simulated data. Target locations were always accurately determined. Error in optical strength estimates was small even at 20% noise level. Target size and shape were more sensitive to noise. Results from simulated data demonstrate high potential for application of TROT in practical biomedical imaging applications.

Citation Download Citation

Binlin Wu, W. Cai, M. Xu, and S. K. Gayen "Time-reversal optical tomography: detecting and locating extended targets in a turbid medium", Proc. SPIE 8216, Multimodal Biomedical Imaging VII, 82160K (29 February 2012); https://doi.org/10.1117/12.906799

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available