Monitoring the effect of dextran on blood sedimentation using a pulsed photoacoustic technique

Matti Kinnunen

doi:10.1117/12.914761

9 February 2012 Monitoring the effect of dextran on blood sedimentation using a pulsed photoacoustic technique

Matti Kinnunen

Proceedings Volume 8222, Dynamics and Fluctuations in Biomedical Photonics IX; 82221E (2012) https://doi.org/10.1117/12.914761
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

The capabilities of a pulsed photoacoustic technique for monitoring blood sedimentation and red blood cell (RBC) aggregation were tested in a cuvette in vitro. Diluted blood samples with concentrations of 40% and 60% were used. In addition, the effect of dextran (T500) was investigated with blood concentrations of 40% and 60%. Optical coherence tomography was used in parallel to visualize the sedimentation process. The results show that a 1 MHz acoustic transducer can be used to detect PA signals from blood in vitro during sedimentation, and the acoustic pulse delay is a good indicator for following the sedimentation process. Dextran greatly accelerated the sedimentation process.

Citation Download Citation

Matti Kinnunen "Monitoring the effect of dextran on blood sedimentation using a pulsed photoacoustic technique", Proc. SPIE 8222, Dynamics and Fluctuations in Biomedical Photonics IX, 82221E (9 February 2012); https://doi.org/10.1117/12.914761

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