The study of quantitative optical absorption imaging by using Monte Carlo simulation of combined photoacoustic tomography and ultrasound-modulated optical tomography

Chulhong Kim; Yang Li; Lihong V. Wang

doi:10.1117/12.905792

23 February 2012 The study of quantitative optical absorption imaging by using Monte Carlo simulation of combined photoacoustic tomography and ultrasound-modulated optical tomography

Chulhong Kim, Yang Li, Lihong V. Wang

Author Affiliations +

Proceedings Volume 8223, Photons Plus Ultrasound: Imaging and Sensing 2012; 82232C (2012) https://doi.org/10.1117/12.905792
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

We demonstrate the feasibility of quantitative optical absorption imaging by using Monte Carlo simulation of combined photoacoustic tomography (PAT) and ultrasound-modulated optical tomography (UOT). Our simulation results show that the optical fluence on initial photoacoustic (PA) pressure waves can be accurately compensated for recovering exact optical absorption coefficients by using a fluence map acquired from UOT signals. Further, when the optical heterogeneities of a sample were varied, the recovered optical absorption coefficients from a target remained constant while PA amplitudes fluctuated. In practice, PAT and UOT systems can be potentially combined because both imaging systems can easily share light illumination and ultrasound application patterns.

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Chulhong Kim, Yang Li, and Lihong V. Wang "The study of quantitative optical absorption imaging by using Monte Carlo simulation of combined photoacoustic tomography and ultrasound-modulated optical tomography", Proc. SPIE 8223, Photons Plus Ultrasound: Imaging and Sensing 2012, 82232C (23 February 2012); https://doi.org/10.1117/12.905792

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