Plasmonic nanobubbles for cell theranostics

Ekaterina Y. Lukianova-Hleb; Shruti Kashinath; Dmitri O. Lapotko

doi:10.1117/12.910639

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6 February 2012 Plasmonic nanobubbles for cell theranostics

Ekaterina Y. Lukianova-Hleb, Shruti Kashinath, Dmitri O. Lapotko

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Proceedings Volume 8234, Plasmonics in Biology and Medicine IX; 82341F (2012) https://doi.org/10.1117/12.910639
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

A novel transient nanoprobe was developed whose biomedical functions can be dynamically and selectively tuned inside living cells. This probe is not a nanoparticle, but a transient event, a vapor nanobubble generated with a laser pulse around gold (plasmonic) nanoparticles. This is a phenomenon that we recently discovered and named plasmonic nanobubbles (PNBs). PNBs represent an entirely new class of probes due to their dynamic tunability in situ, including single cells. We show that PNB provides highly sensitive diagnosis and immediate follow-up and guided treatment with true nanoscale precision at the level of single cells.

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Ekaterina Y. Lukianova-Hleb, Shruti Kashinath, and Dmitri O. Lapotko "Plasmonic nanobubbles for cell theranostics", Proc. SPIE 8234, Plasmonics in Biology and Medicine IX, 82341F (6 February 2012); https://doi.org/10.1117/12.910639

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