A bio-aerosol detection technique based on tryptophan intrinsic fluorescence measurement

Shuyao Cai; Pei Zhang; Linglin Zhu; Yongkai Zhao; Huijie Huang

doi:10.1117/12.920766

29 November 2011 A bio-aerosol detection technique based on tryptophan intrinsic fluorescence measurement

Shuyao Cai, Pei Zhang, Linglin Zhu, Yongkai Zhao, Huijie Huang

Proceedings Volume 8311, Optical Sensors and Biophotonics III; 83110X (2011) https://doi.org/10.1117/12.920766
Event: SPIE/OSA/IEEE Asia Communications and Photonics, 2011, Shanghai, China

Abstract

Based on the measurement of intrinsic fluorescence, a set of bio-aerosol including virus aerosols detection instrument is developed, with which a method of calibration is proposed using tryptophan as the target. The experimental results show a good linear relationship between the fluorescence voltage of the instrument and the concentration of the tryptophan aerosol. An excellent correlation (R²≥0.99) with the sensitivity of 4000PPL is obtained. The research demonstrates the reliability of the bio-aerosol detection by measuring the content of tryptophan. Further more the feasibility of prejudgment to the species of bio-aerosol particles with the multi-channel fluorescence detection technology is discussed.

Citation Download Citation

Shuyao Cai, Pei Zhang, Linglin Zhu, Yongkai Zhao, and Huijie Huang "A bio-aerosol detection technique based on tryptophan intrinsic fluorescence measurement", Proc. SPIE 8311, Optical Sensors and Biophotonics III, 83110X (29 November 2011); https://doi.org/10.1117/12.920766

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