Quantitative DEC-MRI modeling on tumor diagnosis and treatment effect evaluation

Haoyu Wang; Shanglian Bao

doi:10.1117/12.901249

29 November 2011 Quantitative DCE-MRI modeling on tumor diagnosis and treatment effect evaluation

Haoyu Wang, Shanglian Bao

Proceedings Volume 8311, Optical Sensors and Biophotonics III; 83110Y (2011) https://doi.org/10.1117/12.901249
Event: SPIE/OSA/IEEE Asia Communications and Photonics, 2011, Shanghai, China

Abstract

Dynamic contrast enhanced (DCE) MRI is the method of choice for clinical tumor detection. There are three categories of DCE-MRI analysis methods including qualitative DCE-MRI, semi-quantitative DCE-MRI, and quantitative DCE-MRI. Among these three categories, quantitative DCE-MRI is the only one that could provide pharmacokinetic parameters and directly reveal physiological state of tumor. In this paper, we have made a brief review on quantitative DCE-MRI. Firstly, physiological basis of DCE-MRI was described in details. Then, two kinds of contrast agent, low molecular weighted contrast media (LMCM) and macromolecular contrast media (MMCM), are introduced respectively. After that, several T1 weighted DCE-MRI data analysis methods are introduced, too. At last, possible further developments of DCE-MRI have been discussed.

Citation Download Citation

Haoyu Wang and Shanglian Bao "Quantitative DCE-MRI modeling on tumor diagnosis and treatment effect evaluation", Proc. SPIE 8311, Optical Sensors and Biophotonics III, 83110Y (29 November 2011); https://doi.org/10.1117/12.901249

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