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23 February 2012Computer-aided marginal artery detection on computed tomographic colonography
Computed tomographic colonography (CTC) is a minimally invasive technique for colonic polyps and cancer
screening. The marginal artery of the colon, also known as the marginal artery of Drummond, is the blood
vessel that connects the inferior mesenteric artery with the superior mesenteric artery. The marginal artery
runs parallel to the colon for its entire length, providing the blood supply to the colon. Detecting the marginal
artery may benefit computer-aided detection (CAD) of colonic polyp. It can be used to identify teniae coli
based on their anatomic spatial relationship. It can also serve as an alternative marker for colon localization,
in case of colon collapse and inability to directly compute the endoluminal centerline. This paper proposes an
automatic method for marginal artery detection on CTC. To the best of our knowledge, this is the first work
presented for this purpose. Our method includes two stages. The first stage extracts the blood vessels in the
abdominal region. The eigenvalue of Hessian matrix is used to detect line-like structures in the images. The
second stage is to reduce the false positives in the first step. We used two different masks to exclude the false
positive vessel regions. One is a dilated colon mask which is obtained by colon segmentation. The other is an
eroded visceral fat mask which is obtained by fat segmentation in the abdominal region. We tested our
method on a CTC dataset with 6 cases. Using ratio-of-overlap with manual labeling of the marginal artery as
the standard-of-reference, our method yielded true positive, false positive and false negative fractions of 89%,
33%, 11%, respectively.