Active relearning for robust supervised classification of pulmonary emphysema

Sushravya Raghunath; Srinivasan Rajagopalan; Ronald A. Karwoski; Brian J. Bartholmai; Richard A. Robb

doi:10.1117/12.911648

23 February 2012 Active relearning for robust supervised classification of pulmonary emphysema

Sushravya Raghunath, Srinivasan Rajagopalan, Ronald A. Karwoski, Brian J. Bartholmai, Richard A. Robb

Proceedings Volume 8315, Medical Imaging 2012: Computer-Aided Diagnosis; 83152Q (2012) https://doi.org/10.1117/12.911648
Event: SPIE Medical Imaging, 2012, San Diego, California, United States

Abstract

Radiologists are adept at recognizing the appearance of lung parenchymal abnormalities in CT scans. However, the inconsistent differential diagnosis, due to subjective aggregation, mandates supervised classification. Towards optimizing Emphysema classification, we introduce a physician-in-the-loop feedback approach in order to minimize uncertainty in the selected training samples. Using multi-view inductive learning with the training samples, an ensemble of Support Vector Machine (SVM) models, each based on a specific pair-wise dissimilarity metric, was constructed in less than six seconds. In the active relearning phase, the ensemble-expert label conflicts were resolved by an expert. This just-in-time feedback with unoptimized SVMs yielded 15% increase in classification accuracy and 25% reduction in the number of support vectors. The generality of relearning was assessed in the optimized parameter space of six different classifiers across seven dissimilarity metrics. The resultant average accuracy improved to 21%. The co-operative feedback method proposed here could enhance both diagnostic and staging throughput efficiency in chest radiology practice.

Citation Download Citation

Sushravya Raghunath, Srinivasan Rajagopalan, Ronald A. Karwoski, Brian J. Bartholmai, and Richard A. Robb "Active relearning for robust supervised classification of pulmonary emphysema", Proc. SPIE 8315, Medical Imaging 2012: Computer-Aided Diagnosis, 83152Q (23 February 2012); https://doi.org/10.1117/12.911648

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