Age and gender related differences in aortic blood flow

Marie Sand Enevoldsen; Mads Møller Pedersen; Martin Christian Hemmsen; Lars Lönn; Kaj-Åge Henneberg; Jørgen Arendt Jensen

doi:10.1117/12.910859

24 February 2012 Age and gender related differences in aortic blood flow

Marie Sand Enevoldsen, Mads Møller Pedersen, Martin Christian Hemmsen, Lars Lönn, Kaj-Åge Henneberg, Jørgen Arendt Jensen

Author Affiliations +

Proceedings Volume 8320, Medical Imaging 2012: Ultrasonic Imaging, Tomography, and Therapy; 83200J (2012) https://doi.org/10.1117/12.910859
Event: SPIE Medical Imaging, 2012, San Diego, California, United States

Abstract

The abdominal aorta (AA) is predisposed to development of abdominal aneurysms (AAA), a focal dilatation with fatal consequences if left untreated. The blood flow patterns is thought to play an important role in the development of AAA. The purpose of this work is to investigate the blood flow patterns within a group of healthy volunteers (six females, eight males) aged 23 to 76 years to identify changes and differences related to age and gender. The healthy volunteers were categorized by gender (male/female) and age (below/above 35 years). Subject-specific flow and geometry data were acquired using the research interface on a Profocus ultrasound scanner (B-K Medical, Herlev, Denmark) and segmentation of 3D magnetic resonance angiography (Magnetom Trio, Siemens Healthcare, Erlangen, Germany). The largest average diameter was among the elderly males (19.7 (± 1.33) mm) and smallest among the young females (12.4 (± 0.605) mm). The highest peak systolic velocity was in the young female group (1.02 (± 0.336) m/s) and lowest in the elderly male group (0.836 (± 0.127) m/s). A geometrical change with age was observed as the AA becomes more bended with age. This also affects the blood flow velocity patterns, which are markedly different from young to elderly. Thus, changes in blood flow patterns in the AA related to age and gender are observed. Further investigations are needed to determine the relation between changes in blood flow patterns and AAA development.

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Marie Sand Enevoldsen, Mads Møller Pedersen, Martin Christian Hemmsen, Lars Lönn, Kaj-Åge Henneberg, and Jørgen Arendt Jensen "Age and gender related differences in aortic blood flow", Proc. SPIE 8320, Medical Imaging 2012: Ultrasonic Imaging, Tomography, and Therapy, 83200J (24 February 2012); https://doi.org/10.1117/12.910859

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KEYWORDS

Blood circulation

Magnetic resonance imaging

Data acquisition

Image segmentation

Ultrasonography

Blood

Arteries

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