Liver cancer or hepatocellular carcinoma (HCC) is a serious malady with only 10% survival rate. HCC incidence and
mortality both are highest in China. This disease is detected and diagnosed by ultra sound, CT or MRI scans which are
quite expensive. Also the discrimination between cirrhosis and HCC are poor by this imaging technique. The
conventional tissue biopsy is quite invasive and painful. In this context, in the new diagnostic procedure presented in this
paper, all the three liver malfunctions, particularly liver cancer, could be detected and discriminated by the spectral
feature of blood and urine with accuracy about 80%. All that we need are 5 ml of blood and 5 ml of urine. Hence this
inexpensive non invasive, optical technique will have significant impact in screening, diagnosis and also prognosis of
HCC in large segment of people in the populous Asian countries.
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