Development and investigation of flexible polymer neural probe for chronic neural recording

Courtney Smith; Kyo D. Song; Hargsoon Yoon; Woong-Ki Kim; Tao Zeng; Larry D. Sanford

doi:10.1117/12.917481

30 March 2012 Development and investigation of flexible polymer neural probe for chronic neural recording

Courtney Smith, Kyo D. Song, Hargsoon Yoon, Woong-Ki Kim, Tao Zeng, Larry D. Sanford

Proceedings Volume 8344, Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2012; 834404 (2012) https://doi.org/10.1117/12.917481
Event: SPIE Smart Structures and Materials + Nondestructive Evaluation and Health Monitoring, 2012, San Diego, California, United States

Abstract

Neural recording through microelectrodes requires biocompatibility and long term chronic usage. With a potential for various applications and effort to improve the performance of neural recording probes, consideration is taken to the tissue and cellular effects in these device designs. The degeneration of neurons due to brain tissue motion is an issue along with brain tissue inflammation in the insertion of the probes. To account for motion and irritation the material structure of the probes must be improved upon. This research presents the fabrication of neural probes on the microscale utilizing flexible polymers. Polyimide neural probes have been considered possibly to reduce degradation in their variability caused by brain motion. The microfabrication of the polyimide neural probe has an increased flexibility while accounting for biocompatibility and the needs for chronic use. Through microfabrication processes a needle probe is produced and tested for neural recording.

Citation Download Citation

Courtney Smith, Kyo D. Song, Hargsoon Yoon, Woong-Ki Kim, Tao Zeng, and Larry D. Sanford "Development and investigation of flexible polymer neural probe for chronic neural recording", Proc. SPIE 8344, Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2012, 834404 (30 March 2012); https://doi.org/10.1117/12.917481

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