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Micro scale and nano scale technology developments have the potential to revolutionize smart and small systems. The
application of systems engineering methodologies that integrate standalone, small-scale technologies and interface them
with macro technologies to build useful systems is critical to realizing the potential of these technologies. This paper
covers the expanding knowledge base on systems engineering principles for micro and nano technology integration
starting with a discussion of the drivers for applying a systems approach. Technology development on the micro and
nano scale has transition from laboratory curiosity to the realization of products in the health, automotive, aerospace,
communication, and numerous other arenas. This paper focuses on the maturity (or lack thereof) of the field of
nanosystems which is emerging in a third generation having transitioned from completing active structures to creating
systems. The emphasis of applying a systems approach focuses on successful technology development based on the lack
of maturity of current nano scale systems. Therefore the discussion includes details relating to enabling roles such as
product systems engineering and technology development. Classical roles such as acquisition systems engineering are
not covered. The results are also targeted towards small-scale technology developers who need to take into account
systems engineering processes such as requirements definition, verification, and validation interface management and
risk management in the concept phase of technology development to maximize the likelihood of success, cost effective
micro and nano technology to increase the capability of emerging deployed systems and long-term growth and profits.
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