Optical coherence elastography: Strain imaging in tissue using optical coherence tomography

Brendan F. Kennedy; Kelsey M. Kennedy; Chris Ford; Robert A. McLaughlin; Mark B. Bush; David D. Sampson

doi:10.1117/12.975187

17 October 2012 Optical coherence elastography: Strain imaging in tissue using optical coherence tomography

Brendan F. Kennedy, Kelsey M. Kennedy, Chris Ford, Robert A. McLaughlin, Mark B. Bush, David D. Sampson

Proceedings Volume 8421, OFS2012 22nd International Conference on Optical Fiber Sensors; 84211U (2012) https://doi.org/10.1117/12.975187
Event: OFS2012 22nd International Conference on Optical Fiber Sensor, 2012, Beijing, China

Abstract

Optical coherence elastography (OCE) is a strain imaging technique that characterizes the elastic properties of tissues with microscopic resolution in three dimensions. In OCE, the displacement introduced to tissue by mechanical excitation is measured using optical coherence tomography. The local strain is calculated from the spatial derivative of displacement to generate strain images, known as elastograms. To validate elastograms, we compare them to a finite element analysis model of sample deformation. We also present preliminary OCE measurements performed on excised human breast tissue, and demonstrate discrimination of tissue types based on their elastic properties.

Citation Download Citation

Brendan F. Kennedy, Kelsey M. Kennedy, Chris Ford, Robert A. McLaughlin, Mark B. Bush, and David D. Sampson "Optical coherence elastography: Strain imaging in tissue using optical coherence tomography", Proc. SPIE 8421, OFS2012 22nd International Conference on Optical Fiber Sensors, 84211U (17 October 2012); https://doi.org/10.1117/12.975187

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available