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30 April 2012 Plasmonic nanosensors in the treatment of cancer: an attempt to conquer the immortal illness
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In 2011, a survey conducted all over the world says that more than 7 million humans around the world died of cancer. One in three women and one in two men developed cancer during their lifetime. About 15 percent of all deaths worldwide, was attributed to cancer. In some nations, cancer will surpass heart disease to become the most common cause of death. This thesis attempts to conquer this immortal illness. Here, we present a radical platform of cancer treatment based on silver nanoparticle-developed ''conglomerate'' photothermal vapour nanobubbles. These conglomerate plasmonic nanobubbles are capable of diagnosing (by optical scattering technique) and therapeutic action (by mechanical, nonthermal and selective annihilation of target cells) of cancerous cells without affecting adjoining normal cells. At first, theoretical simulation of optical fiber SPR sensors was carried out. Then these nanosensors were designed, fabricated and their sensitivities were measured experimentally. We introduce the nanosensors and describe how their sizes, environments, sensitivities, specificities, efficacies and selectivities can be harnessed to detect and treat cancerous cells. This paper has been written from the quest to launch something that can eradicate this disease from our bodies and societies forever.
© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Saikat Das and Jari Turunen "Plasmonic nanosensors in the treatment of cancer: an attempt to conquer the immortal illness", Proc. SPIE 8424, Nanophotonics IV, 842416 (30 April 2012);

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