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11 December 2012 Optical characters of prostate using nonlinear optical microscopy
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The incidence rate of the prostatic hyperplasia is increasing in near decade, early detection is important for preventing the prostatic cancer (PCa). In this study, the images of prostate and cavernous nerves were carried out using intrinsic fluorescence and scattering properties of the tissues without any exogenous dye or contrast agent based on nonlinear optical microscope. The texture feature and optical property of the interfibrillar substance in prostate tissue were extracted and analyzed for charactering the prostate structure. It will be the feature parameter to differentiate the normal, the inflammation or cancer of prostate tissue in clinical with the application of miniature endoscope nonlinear optical microscope in vivo.
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Shulian Wu, Hui Li, Xiaoman Zhang, Yunxia Wang, and Dongqing Peng "Optical characters of prostate using nonlinear optical microscopy", Proc. SPIE 8553, Optics in Health Care and Biomedical Optics V, 85532N (11 December 2012);

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