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6 March 2013A fiber tip label free biological sensing platform for in vivo applications
The novel platform presented in this paper is design to answer the unmet challenge of real time label free in-vivo sensing
by bringing together a refractive index transducing mechanism based on Whispering Gallery Modes in dye doped
microspheres combined with Microstructured Optical Fibers. In addition to providing the provides the remote excitation
and collection of the WGM signal, the fibre also allows easily manipulation of the microresonator and the use this sensor
in a dip sensing architecture, alleviating the need for a complex microfluidic interface. Here, we demonstrate the ability
of this sensing platform to be operated above its lasing threshold, enabling enhanced performance.
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A. François, K. J. Rowland, T. M. Monro, "A fiber tip label free biological sensing platform for in vivo applications," Proc. SPIE 8570, Frontiers in Biological Detection: From Nanosensors to Systems V, 85700F (6 March 2013); https://doi.org/10.1117/12.2003612