A fiber tip label free biological sensing platform for in vivo applications

A. François; K. J. Rowland; T. M. Monro

doi:10.1117/12.2003612

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6 March 2013 A fiber tip label free biological sensing platform for in vivo applications

A. François, K. J. Rowland, T. M. Monro

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Proceedings Volume 8570, Frontiers in Biological Detection: From Nanosensors to Systems V; 85700F (2013) https://doi.org/10.1117/12.2003612
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

The novel platform presented in this paper is design to answer the unmet challenge of real time label free in-vivo sensing by bringing together a refractive index transducing mechanism based on Whispering Gallery Modes in dye doped microspheres combined with Microstructured Optical Fibers. In addition to providing the provides the remote excitation and collection of the WGM signal, the fibre also allows easily manipulation of the microresonator and the use this sensor in a dip sensing architecture, alleviating the need for a complex microfluidic interface. Here, we demonstrate the ability of this sensing platform to be operated above its lasing threshold, enabling enhanced performance.

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A. François, K. J. Rowland, and T. M. Monro "A fiber tip label free biological sensing platform for in vivo applications", Proc. SPIE 8570, Frontiers in Biological Detection: From Nanosensors to Systems V, 85700F (6 March 2013); https://doi.org/10.1117/12.2003612

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