Tapered optical fibers for aqueous and gaseous phase biosensing applications

Branden J. King; Ighodalo Idehenre; Peter E. Powers; Andrew M. Sarangan; Joseph W. Haus; Karolyn M. Hansen

doi:10.1117/12.2004799

5 March 2013 Tapered optical fibers for aqueous and gaseous phase biosensing applications

Branden J. King, Ighodalo Idehenre, Peter E. Powers, Andrew M. Sarangan, Joseph W. Haus, Karolyn M. Hansen

Proceedings Volume 8570, Frontiers in Biological Detection: From Nanosensors to Systems V; 85700G (2013) https://doi.org/10.1117/12.2004799
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

This study focuses on the design, fabrication and characterization of a tapered optical fiber platform for the label-free detection of aqueous and gaseous biomolecules. Single mode fibers were tapered to a diameter of approximately 10 microns, and this tapered surface was functionalized with biomolecules for aqueous (antibody) detection of analytes. Molecular binding to the surface changes the refractive index and thickness of the biolayer, which interacts with propagating light, causing a measureable phase shift in the output.

Citation Download Citation

Branden J. King, Ighodalo Idehenre, Peter E. Powers, Andrew M. Sarangan, Joseph W. Haus, and Karolyn M. Hansen "Tapered optical fibers for aqueous and gaseous phase biosensing applications", Proc. SPIE 8570, Frontiers in Biological Detection: From Nanosensors to Systems V, 85700G (5 March 2013); https://doi.org/10.1117/12.2004799

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