Chromatic visualization of reflectivity variance within hybridized directional OCT images

Vikram S. Makhijani; Austin Roorda; Jan Kristine Bayabo; Kevin K. Tong; Carlos A. Rivera-Carpio; Brandon J. Lujan

doi:10.1117/12.2007141

20 March 2013 Chromatic visualization of reflectivity variance within hybridized directional OCT images

Vikram S. Makhijani, Austin Roorda, Jan Kristine Bayabo, Kevin K. Tong, Carlos A. Rivera-Carpio, Brandon J. Lujan

Proceedings Volume 8571, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII; 857105 (2013) https://doi.org/10.1117/12.2007141
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

This study presents a new method of visualizing hybridized images of retinal spectral domain optical coherence tomography (SDOCT) data comprised of varied directional reflectivity. Due to the varying reflectivity of certain retinal structures relative to angle of incident light, SDOCT images obtained with differing entry positions result in nonequivalent images of corresponding cellular and extracellular structures, especially within layers containing photoreceptor components. Harnessing this property, cross-sectional pathologic and non-pathologic macular images were obtained from multiple pupil entry positions using commercially-available OCT systems, and custom segmentation, alignment, and hybridization algorithms were developed to chromatically visualize the composite variance of reflectivity effects. In these images, strong relative reflectivity from any given direction visualizes as relative intensity of its corresponding color channel. Evident in non-pathologic images was marked enhancement of Henle’s fiber layer (HFL) visualization and varying reflectivity patterns of the inner limiting membrane (ILM) and photoreceptor inner/outer segment junctions (IS/OS). Pathologic images displayed similar and additional patterns. Such visualization may allow a more intuitive understanding of structural and physiologic processes in retinal pathologies.

Citation Download Citation

Vikram S. Makhijani, Austin Roorda, Jan Kristine Bayabo, Kevin K. Tong, Carlos A. Rivera-Carpio, and Brandon J. Lujan "Chromatic visualization of reflectivity variance within hybridized directional OCT images", Proc. SPIE 8571, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII, 857105 (20 March 2013); https://doi.org/10.1117/12.2007141

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available