A time-domain diffuse optical/fluorescent tomography using multi-dimensional TCSPC design

Yiming Lu; Wei Zhang; Linhui Wu; Liming Zhang; Feng Gao

doi:10.1117/12.2001005

22 March 2013 A time-domain diffuse optical/fluorescent tomography using multi-dimensional TCSPC design

Yiming Lu, Wei Zhang, Linhui Wu, Liming Zhang, Feng Gao

Proceedings Volume 8572, Advanced Biomedical and Clinical Diagnostic Systems XI; 85721I (2013) https://doi.org/10.1117/12.2001005
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

Techniques of time-correlated single-photon counting (TCSPC) have been widely used in diffuse optical tomography (DOT) and diffuse fluorescence tomography (DFT). While a multi-channel TCSPC-based DOT/DFT system can be conveniently constructed using independent modules, the state-of-the-art TCSPC technique has extended its multidimensional function by facilitating a compact and cost-effective design of the multi-channel as well as multi-wavelength data-acquisition. We herein present a revised multi-channel TCSPC system that is based the multidimensional function of the TCSPC device. We also design a series of DOT and DFT experiments to validate effectiveness of the system.

Citation Download Citation

Yiming Lu, Wei Zhang, Linhui Wu, Liming Zhang, and Feng Gao "A time-domain diffuse optical/fluorescent tomography using multi-dimensional TCSPC design", Proc. SPIE 8572, Advanced Biomedical and Clinical Diagnostic Systems XI, 85721I (22 March 2013); https://doi.org/10.1117/12.2001005

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