Continuous wave broadband analysis of tissues

Hadi Zabihi Yeganeh; Vladislav Toronov; Mamadou Diop; Jonathon T. Elliott; Keith St. Lawrence; Ting-Yim Lee

doi:10.1117/12.2005486

25 March 2013 Continuous wave broadband analysis of tissues

Hadi Zabihi Yeganeh, Vladislav Toronov, Mamadou Diop, Jonathon T. Elliott, Keith St. Lawrence, Ting-Yim Lee

Proceedings Volume 8578, Optical Tomography and Spectroscopy of Tissue X; 85781C (2013) https://doi.org/10.1117/12.2005486
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

A fundamental problem of separation of absorption and scattering contributions into light attenuation was resolved using time- and frequency-domain systems. In spite of the progress in the development of time- and frequency-domain hardware, continuous-wave systems offer higher signal-to-noise ratios, better portability, and, potentially, lower equipment and service costs. In biological tissues of known composition one can quantify the chromophore concentrations, such as oxy- and deoxyhemoglobin, water, and fat, and also quantify the reduced scattering coefficient by using broadband approach and by employing characteristic spectral features of chromophores. In this submission we report further developments of our hyperspectral technique to measure absolute concentrations of tissue chromophores.

Citation Download Citation

Hadi Zabihi Yeganeh, Vladislav Toronov, Mamadou Diop, Jonathon T. Elliott, Keith St. Lawrence, and Ting-Yim Lee "Continuous wave broadband analysis of tissues", Proc. SPIE 8578, Optical Tomography and Spectroscopy of Tissue X, 85781C (25 March 2013); https://doi.org/10.1117/12.2005486

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KEYWORDS

Tissues

Absorbance

Scattering

Chromophores

Light scattering

Optical properties

Spectroscopy

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