Quantitative imaging of bilirubin by photoacoustic microscopy

Yong Zhou; Chi Zhang; Da-Kang Yao; Lihong V. Wang

doi:10.1117/12.2004394

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4 March 2013 Quantitative imaging of bilirubin by photoacoustic microscopy

Yong Zhou, Chi Zhang, Da-Kang Yao, Lihong V. Wang

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Proceedings Volume 8581, Photons Plus Ultrasound: Imaging and Sensing 2013; 85813A (2013) https://doi.org/10.1117/12.2004394
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

Noninvasive detection of both bilirubin concentration and its distribution is important for disease diagnosis. Here we implemented photoacoustic microscopy (PAM) to detect bilirubin distribution. We first demonstrate that our PAM system can measure the absorption spectra of bilirubin and blood. We also image bilirubin distributions in tissuemimicking samples, both without and with blood mixed. Our results show that PAM has the potential to quantitatively image bilirubin in vivo for clinical applications.

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Yong Zhou, Chi Zhang, Da-Kang Yao, and Lihong V. Wang "Quantitative imaging of bilirubin by photoacoustic microscopy", Proc. SPIE 8581, Photons Plus Ultrasound: Imaging and Sensing 2013, 85813A (4 March 2013); https://doi.org/10.1117/12.2004394

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